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Medicube ZERO PORE ONE DAY PEPTIDE SERUM 30ml

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Original price Rs 1,475.00
Original price Rs 1,475.00 - Original price Rs 1,475.00
Original price Rs 1,475.00
Current price
Rs 1,275.00 VAT included
Rs 1,275.00 - Rs 1,275.00
Current price
Rs 1,275.00 VAT included
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Medicube ZERO PORE ONE DAY PEPTIDE SERUM 30ml ("Zero Pore One Day 10-Peptide Serum" internationally) is the upgraded sibling of the plain One-Day Serum — the same PHA-forward acid base plus a marketed 10-peptide complex and LHA (Capryloyl Salicylic Acid) as a fourth acid, described by the brand as a "quadruple acid" formula, alongside 2% Niacinamide. It works overnight to clear pore congestion chemically while supporting firmness with confirmed peptides Oligopeptide-1/2/3 and Acetyl Octapeptide-3. Do not use it if you are new to chemical exfoliants, currently barrier-compromised, or under 16 — this is the strongest product in the Zero Pore One-Day family.

Important Safety Notice:

This is an active-strength exfoliating treatment combining four acid types with a peptide complex. If your skin currently stings when you apply moisturizer, feels tight within 30 minutes of cleansing, or shows visible flaking, your barrier needs repair first — using this product now will make things worse. See the Safety and Patch Test section below before your first use.

At-a-Glance (Is this for you?)

Values: 100% Genuine* Ā· Fragrance-Free (no Fragrance/Parfum entry found in the declared INCI) Ā· Pregnancy-Caution (not contraindicated, but this is an active-strength product — see Safety Notice) Ā· Halal-Friendly* Ā· Vegan-Friendly*

*Self-assessed by Adilsons based on available INCI data. No ethanol from fermentation, no porcine-derived ingredients, and no haram or animal-derived ingredients detected in the declared ingredient list. This is NOT a formal Halal certification. Muslims with stricter requirements should consult their own scholars. Vegan claim is on the same self-assessed basis — no animal-derived ingredients detected; this is NOT a formal vegan certification.

Attribute Detail
Brand Medicube
Product Type Overnight resurfacing + firming serum
Net Volume 30ml
Key Actives Quadruple acid complex (AHA + BHA + PHA + LHA) + 2% Niacinamide + 10-peptide complex
Skin Types Oily, combination, congested/textured, wanting a firming angle — not for reactive or barrier-compromised skin
Primary Concern Enlarged pores, surface texture, pore/skin firmness
AM/PM Suitability PM only
Routine Complexity Advanced — highest active load in the Zero Pore One-Day family
MFDS Classification Not confirmed as Functional Cosmetic — treated as General Cosmetic

This is the "graduated" version for someone who's already comfortable with the plain One-Day Serum and wants an added firming angle, not a first acid serum.

Pros: confirmed peptide actives (Oligopeptide-1, an EGF-analog signaling peptide, plus Oligopeptide-2/3 and Acetyl Octapeptide-3), a fourth acid (LHA) for broader exfoliation coverage, fragrance-free, shares the base Serum's 2% Niacinamide. Caveats: two marketed peptide names (Copper Tripeptide-1/GHK-Cu, Acetyl Hexapeptide-1) were not confirmed by exact INCI name in this research pass, exact acid percentages for this specific SKU weren't independently re-verified (assumed shared with the base Serum), and reviewers describe the texture as noticeably stickier than the plain Serum.

Age and Tween Suitability (Parental Guide)

Classification: RED. A quadruple-acid complex at an advanced strength (building on the base Serum's 15.2%, plus LHA) is a clinical-grade exfoliating formula, not appropriate for skin under roughly 16 that hasn't developed the sebaceous activity and congestion patterns this product targets.

A gentler starting point: Zero Foam Cleanser 120g (no acids) with PDRN Pink Cica Soothing Toner 250ml — both verified in stock.

Quick Start (60-Second Essentials)

Step 1 — When: PM only, on fully cleansed, dry skin.

Step 2 — How much: 2-3 drops for the full face.

Step 3 — How: Press or pat into skin (do not rub), wait 1-3 minutes given the higher active/peptide density, then moisturizer.

Introduce this as the ONLY new product in your routine. Wait a full 14 days before adding anything else. This isolation window ensures you can identify whether any reaction is caused by this specific product.

AM Routine Guide (Morning sequence)

This is a PM-only product — its quadruple-acid content increases sun sensitivity, and Mauritius's UV index runs high nearly year-round.

A typical AM sequence without this serum: 1) Rinse cleanse, 2) Hydrating toner (optional), 3) Niacinamide/soothing serum (optional), 4) Moisturizer, 5) SPF50+ PA++++, mandatory after any acid night, reapplied every 2 hours outdoors.

PM Routine Guide (Evening sequence)

1) Oil cleanse if wearing sunscreen/makeup, 2) Water cleanser, 3) Optional hydrating toner, 4) Zero Pore One-Day Peptide Serum — 2-3 drops, pressed in, wait 1-3 minutes, 5) Moisturizer, 6) Optional occlusive seal on AC-heavy or very dry nights.

Skin cycling integration: occupies the Exfoliation lane. On a 4-night cycle: Night 1 this serum, Night 2 retinoid (if used), Nights 3-4 recovery.

How to Use (Amounts, technique, and tips)
Area Amount
Full face 2-3 drops

Technique: pat/press, do not rub — friction increases irritation on an already acid-active, peptide-dense serum. Required skin state: fully dry skin. Wait time: 1-3 minutes before moisturizer — a longer window than the plain Serum, since reviewers report this variant sits stickier and needs more time to settle before the next layer.

Hands deliver 100% of product. Cotton pads absorb approximately 30-40%. Use hands, not a pad.

Routine Encyclopedia (Where every product type fits)

This is an encyclopedia map of all product types. You do not use all of these daily. You select modules based on your skin state.

Global rules: viscosity ladder thinnest to thickest, water-phase before oil-phase, treatments before seals. Wait-time defaults: watery layers 10-20s, serum layers 30-60s, before sunscreen 10-15 min if going outdoors. Amount defaults: toner/essence 5-8 drops, serum/ampoule 2-3 drops or 1 pump, eye product ½ rice-grain per eye, gel moisturizer 1-1.5 peas, cream 1-2 peas, occlusive seal rice-grain to pea-size, sunscreen 2-finger rule for face plus 1 finger for neck. Hydrators go on slightly damp skin; exfoliating acids go on dry skin, one lane only. If the routine pills, stings, or feels heavy — reduce layers, don't add more.

AM Maximum Stack: 1) Rinse/gentle cleanse (optional), 2) pH-prep toner (optional), 3) Hydrating toner layers 1-3 (optional), 4) Essence (optional), 5) Mist (optional), 6) Booster/soothing serum (optional), 7) Antioxidant lane — choose ONE, 8) Pigment support lane — choose ONE, 9) Hydration serum lane, 10) Oil-control lane — choose ONE, 11) Peptide/growth-factor lane, 12) Eye product, 13) Moisturizer, 14) Optional sealing layer (dry/AC only), 15) Sunscreen SPF50+ PA++++ (non-negotiable), 16) Lip SPF (optional). In AM, prioritize comfort and SPF adherence over stacking.

PM Maximum Stack: 1) Micellar pre-cleanse (optional), 2) Oil cleanser (if SPF/makeup worn), 3) Water cleanser, 4) pH-prep toner (optional), 5) Hydrating toner layers (optional), 6) Soothing/barrier serum (optional), 7) [Anchor Product — Zero Pore One-Day Peptide Serum], wait 1-3 minutes given the acid/peptide combination, 8) Targeted serum (optional, only if non-conflicting), 9) Moisturizer, 10) Sleeping mask (optional), 11) Occlusive seal (optional), 12) Spot treatment (as needed), 13) Lip sleeping mask (optional). Do not layer retinoids with AHA/BHA in the same night; keep "one lane" per night.

One-lane rule: Retinoid OR Exfoliation OR Strong Vitamin C (LAA) OR Acne-control active per routine; barrier/hydration can always accompany. If unsure, default to the safest lane and reduce layers.

Viscosity and Layering Science (Where it fits)

This is a water-thin to light-fluid gel-serum — apply after any watery toner/essence and before moisturizer. It sits in the water phase; the Dimethicone and Cetyl Palmitate fractions give a smoothing, slightly richer finish than the plain Serum, consistent with reviewer reports of a stickier texture.

Phase compatibility: water-phase — always layer this before any oil or heavier silicone-forward product.

Weekly Planner (Scheduling actives)
Day AM PM
Mon Hydrate + SPF Zero Pore One-Day Peptide Serum
Tue Hydrate + SPF Recovery — barrier only
Wed Hydrate + SPF Zero Pore One-Day Peptide Serum
Thu Hydrate + SPF Recovery
Fri Hydrate + SPF Zero Pore One-Day Peptide Serum
Sat-Sun Hydrate + SPF Recovery

Rest days: at least 3-4 nights per week with zero acids. Overuse warning: given this is the strongest formula in the family (four acids, not three), nightly use is more likely than the plain Serum to produce barrier damage — cap at 3x/week if this is your first time using this specific product.

What to Expect (Results timeline)
Phase Timeframe What You Will Notice
Immediate 0-24h Smoother texture on touch, possible mild tingling
Adjustment Week 1-2 Possible flaking/tightness; discontinue if burning persists beyond 30 seconds
Epidermal Turnover Week 4-6 Reduced visible congestion, aligned with one full turnover cycle
Dermal Remodeling Week 8-16 Firmness-related peptide effects (if any) would show here, since peptide signaling works on a slower timeline than surface exfoliation
Maintenance Plateau Ongoing Results stabilize at planned frequency; don't increase chasing more

Purging vs. Reaction: PURGING appears in usual breakout zones, stays surface-level, resolves in 4-6 weeks. A REACTION appears in NEW areas, involves burning/swelling/hives, and worsens rather than improves — stop immediately if you see this pattern.

Who Should Use This (Clinical triage)

Before starting this product, your routine MUST already include: a consistent daily SPF habit, a gentle cleanser, a plain moisturizer you tolerate well, and ideally prior experience with the plain One-Day Serum or an equivalent acid product. Without these foundations, this is the wrong entry point.

Status Criteria
PROCEED IF Already tolerates AHA/BHA/PHA acids well, consistent SPF user, not pregnant, age 16+
PAUSE IF New to acid exfoliants generally — start with the plain One-Day Serum first
STOP/CONSULT IF Active eczema/psoriasis, pregnant/nursing and cautious about actives, on prescription retinoids, known salicylate allergy

Graduation/demotion ladder: if this is too strong, step down to Zero Pore One-Day Serum (same base without the fourth acid/peptide complex) — verified in stock.

Barrier index gate: if your skin stings on moisturizer or shows visible flaking, your barrier is below threshold. Start with PDRN Pink Hyaluronic Moisturizing Cream for 1-2 weeks first.

Skin Type Compatibility
Skin Type Compatibility Notes
Oily, experienced with actives Good Primary intended user
Combination Good with caution Spot-apply on T-zone if outer cheeks are drier
Dry Caution Reduce frequency and always follow with a rich moisturizer
New to acids Not recommended Start with the plain One-Day Serum first — this is the advanced tier
Sensitive/reactive Not recommended Highest acid load in the family
Targeted Concerns (What it treats)

Enlarged pores and texture: the quadruple-acid complex (AHA, BHA, PHA, and LHA) dissolves congestion at multiple depths — LHA in particular is a larger-molecule salicylic-acid derivative that's gentler than plain BHA while still working inside the pore. Firmness support: the confirmed peptide fraction (Oligopeptide-1, an EGF-analog signaling peptide, plus Oligopeptide-2/3 and Acetyl Octapeptide-3) is marketed to support the look of skin firmness around stretched pore openings.

What this product cannot do: it cannot physically shrink pore diameter or replace the structural collagen support of a dedicated firming/anti-aging routine — peptide signaling from a leave-on serum is a supportive input, not a substitute for that.

Best Paired With (Synergistic pairings)

1. PDRN Pink Hyaluronic Moisturizing Cream 50ml — follows this serum to replace drawn-out moisture; PM, always after. Alternates: Zero Pore One-Day Cream (same family), PDRN Pink Collagen Capsule Cream, Exosome Cica Cream.

2. Zero Pore Moisture Sun Serum 50ml — mandatory next-morning SPF. Alternates: Collagen Firming Sun Cream, Glow Collagen Sunscreen, PDRN Hydrating UV Serum.

3. Zero Foam Cleanser 120g — gentle, acid-free cleanse keeps total irritation load manageable. Alternates: Zero Pore Clearing Capsule Cleansing Foam, PDRN Hydrating Gel Cleanser, PDRN Pink Niacinamide Whip Cleanser.

4. PDRN Pink Cica Soothing Toner 250ml — calming on recovery nights. Alternates: PDRN Pink Niacinamide Milky Toner, Zero Pore Pad Mild.

Conflict Solver (Active-ingredient rules)

This is a conflict-solver for ACTIVE ingredients. If you run multiple actives, use these rules to avoid irritation, deactivation, and barrier damage.

Universal rule — One Active Lane per routine: run only this serum's exfoliation lane in a single PM routine, not a second strong acid or retinoid the same night.

Ɨ Retinoids: never same night — use skin cycling or alternate nights instead.

Ɨ L-Ascorbic Acid Vitamin C: don't layer in the same routine, consistent with the base Serum's own brand instruction not to combine with Vitamin C products. Use the classic split: Vitamin C AM, this serum PM.

Ɨ A second AHA/BHA/PHA product (e.g. Zero Pore Pad 2.0): avoid stacking two strong exfoliants same night.

Worth flagging honestly: this product's OWN formula already combines direct acids with a marketed peptide complex (including a claimed copper peptide) in one leave-on step. Per general ingredient-conflict guidance, direct acids and copper peptides are normally kept in separate routine steps because low pH can destabilize peptide bonds — this is Medicube's own formulation engineering choice, not something Adilsons can correct, and it means you should NOT then layer a second, separate peptide serum (like Hyaluronic Multi Peptide Serum) immediately after this one; space them to different nights instead.

Scheduling Template (AM/PM Split): AM — antioxidant lane (Vitamin C) → moisturizer → SPF. PM — this serum (exfoliation lane) → moisturizer. Skin-cycling: Night 1 exfoliation (this serum), Night 2 retinoid, Nights 3-4 recovery.

Do not layer retinoids with AHA/BHA in the same night; keep "one lane" per night. One-lane rule: Retinoid OR Exfoliation OR Strong Vitamin C (LAA) OR Acne-control active per routine; barrier/hydration can always accompany.

Hormonal Cycle Synchronization
Phase Days Skin Behavior Use This Product?
Follicular 1-13 Rising estrogen, calmer skin Good window for full planned frequency
Luteal 17-28 Progesterone rises, sebum increases, pores feel congested Keep to planned frequency, don't add extra nights
Menstrual 1-5 (overlap) Skin often more reactive Consider a recovery night if skin feels reactive

Pre-period breakouts happen because progesterone causes the pore lining to physically swell, narrowing the opening and trapping sebum beneath — resist the urge to overuse this serum during the luteal phase; overuse compounds rather than solves this.

Wudu and Prayer Compatibility

Water-Permeable. A light, water-based gel-serum with only minor Dimethicone/Cetyl Palmitate fractions — it does not form a continuous film that blocks water contact with skin.

Applied and absorbed as directed, water should reach the skin normally during wudu. Adilsons provides this assessment based on the product's physical properties. Rulings on wudu validity vary between scholars. Consult your own trusted Islamic authority.

Myth Replacement (Common misconceptions)

MYTH: "More acids (quadruple vs. triple) always means better results." REALITY: LHA is specifically chosen for being gentler than plain salicylic acid, not stronger — the fourth acid broadens the exfoliation profile rather than simply intensifying it.

MYTH: "If it has peptides, it works like an injectable." REALITY: topical peptides in a leave-on serum act as surface signaling molecules with a much lower and slower effect than an injectable — a supportive input, not a dermatologist-procedure replacement.

Climate Fit for Mauritius
Season Conditions Adjustment
Summer (Dec-Mar) High heat, humidity, sweat Sebum rises — SPF discipline the morning after is non-negotiable
Winter (Jun-Sep) Cooler, drier air Reduce to 2x/week if skin feels tighter than usual

AC environment warning: this serum's hyaluronic acid content can draw moisture FROM deeper skin layers in prolonged AC — always seal with a proper moisturizer afterward.

Complete Ingredient Transparency
Ingredient Concentration Evidence Grade Mechanism Source
Gluconolactone (PHA) Not independently re-verified for this SKU (shared base assumed) Strong Large-molecule gentle exfoliant Synthetic
Niacinamide 2% Strong Sebum regulation, barrier support Synthetic
Oligopeptide-1 Not disclosed Emerging* EGF-analog signaling peptide, supports cell turnover signaling Synthetic (biotech)
Oligopeptide-2/3, Acetyl Octapeptide-3 Not disclosed Emerging* Marketed firmness-support signaling peptides Synthetic (biotech)
Centella Asiatica Extract Not disclosed* Emerging* Soothing support Plant

*These ingredients appear below the estimated 1% line in the INCI list, suggesting a trace/sub-efficacious concentration for direct clinical effect, though peptides are conventionally dosed at well under 1% even when functionally active — trace position does not automatically mean ineffective for this ingredient class specifically.

Full INCI: Water(Aqua), Gluconolactone, Methylpropanediol, Glycerin, Propanediol, Tromethamine, Polyglycerin-3, Niacinamide, 1,2-Hexanediol, Citric Acid, Dimethicone, Butylene Glycol, Hydroxyethylcellulose, Salicylic Acid, Sodium Polyacryloyldimethyl Taurate, Lecithin, Allantoin, Lactic Acid, Glycolic Acid, [--- Estimated 1% Line ---] Ethylhexylglycerin, Adenosine, Dextrin, Sodium Hyaluronate, Sodium Citrate, Hemerocallis Fulva Flower Extract, Gardenia Florida Fruit Extract, Trisodium Phosphate, Myosotis Sylvatica Flower/Leaf/Stem Extract, Lactobacillus Ferment Lysate, Taraxacum Officinale (Dandelion) Leaf Extract, Pinus Palustris Leaf Extract, Hydroxypropyltrimonium Hyaluronate, Oenothera Biennis (Evening Primrose) Flower Extract, Acetyl Dipeptide-1 Cetyl Ester, Pentylene Glycol, Caprylyl Glycol, Stellaria Media (Chickweed) Extract, C12-14 Alketh-12, Oligopeptide-2, Oligopeptide-3, Cetyl Palmitate, Indigofera Tinctoria Extract, Lactobacillus Ferment, Oligopeptide-1, Folic Acid, Acetyl Octapeptide-3, Centella Asiatica Extract.

This list is a WebSearch-reconstruction (YesStyle/Korean Beautys listings; direct fetch blocked by network egress) and is INCOMPLETE: brand/Amazon marketing names Copper Tripeptide-1 (GHK-Cu), Acetyl Hexapeptide-1, and LHA (Capryloyl Salicylic Acid) as part of this formula, but none of those three appear by exact INCI name in the list captured this round — an unresolved marketing-vs-INCI gap, not silently assumed present. The 1% line placement is an estimate.

Preservative system: 1,2-Hexanediol and Ethylhexylglycerin, plus Caprylyl Glycol and Pentylene Glycol — a multifunctional glycol-based preservative system, not parabens or formaldehyde-releasers.

Allergens and Fragrance Disclosure

Fragrance status: Fragrance-Free — no Fragrance/Parfum entry appears in the reconstructed declared INCI, consistent with the base Serum.

EU 26 allergen screen: None detected in the declared INCI.

Alcohol disclosure: Alcohol-Free — no denatured or drying alcohol identified.

Cross-Reactivity and Drug Interactions

Aspirin sensitivity → Salicylic Acid (BHA) and LHA (a salicylic-acid derivative): this serum contains both a direct BHA and a marketed LHA (Capryloyl Salicylic Acid) — individuals with a genuine salicylate allergy should be extra cautious here versus the plain Serum, since this variant's total salicylate-family exposure is likely higher.

Prescription interactions: if you use prescription tretinoin, adapalene, or isotretinoin, consult your dermatologist before combining — this is the strongest product in the family.

Conscious and Permissible Formulation

Halal: Self-assessed by Adilsons based on available INCI data. No ethanol from fermentation, no porcine-derived ingredients, and no haram animal-derived ingredients detected in the declared ingredient list. This is NOT a formal Halal certification. Muslims with stricter requirements should consult their own scholars.

Vegan: Self-assessed by Adilsons based on available INCI data. No animal-derived ingredients detected in the reconstructed INCI, including the synthetic/biotech peptide fraction; this is NOT a formal vegan certification.

Cruelty-free: Brand-stated policy. Not independently certified by Leaping Bunny, PETA, or equivalent third-party audit. Brand states cruelty-free, but sells products in Mainland China retail where post-market animal testing may be required by law. Cross-border e-commerce sales may be exempt.

Microplastic-Free: Yes — no known microplastic-classified polymers identified in the declared INCI.

Evidence, Regulation and Claims

MFDS classification: not confirmed as Functional Cosmetic — treated as General Cosmetic.

Clinical claim: the brand carries over the same "10.8% reduction in pore appearance after one day" figure marketed for the plain Serum. No separate, peptide-specific clinical figure was found for this upgraded formula, and no study institution, sample size, or methodology was found for the shared figure either.

*This claim is Marketing-Only tier. Treat the pore-reduction number as the same one used for the base Serum, not a distinct result for the peptide upgrade.

Product Identity and Provenance
Attribute Detail
English Name Zero Pore One-Day 10-Peptide Serum
Brand Medicube
Product Line Zero Pore (One-Day sub-family — upgraded/peptide variant)
Country of Manufacture South Korea
Net Volume 30ml
Sensory and Chemical Profile
Attribute Detail
Texture Water-thin to light gel-serum
Viscosity Light fluid
pH Not publicly disclosed
Finish Reviewers describe it as noticeably stickier than the plain Serum, better suited to a PM-only, no-makeup-after routine

Fungal Acne Safety: FA-Conditional. Cetyl Palmitate, present in this formula (not in the plain Serum), is a fatty acid ester some community FA-trackers flag as conditional. The remaining formula (Dimethicone, C12-14 Alketh-12) carries low general FA concern.

Pilling Risk and Texture Mechanics

Assessment: Medium. The added peptide/ester load versus the plain Serum makes this variant somewhat more prone to pilling under a heavy cream applied too soon.

Mitigation: apply on fully dry skin, wait the full 1-3 minutes, and pat rather than rub the next layer on.

Stability, Spoilage and Oxidation

Fresh product should be clear to very slightly opalescent, similar to the plain Serum. Yellowing, a noticeably darker tint, or separation signals the formula has broken down — discard rather than use.

Storage: keep away from direct bathroom-shelf heat and humidity in Mauritius; peptides are generally more heat-sensitive than simple acids, so cooler storage genuinely helps here.

Spoilage signs: color change, separation that won't remix, an off or sour smell. When in doubt, discard.

Safety and Patch Test Protocol

Patch test: inner forearm for 24 hours, then behind the ear for 24 hours, then begin facial use at reduced frequency (1x/week) for the first two weeks — especially important given this is the strongest product in the family.

If adverse reaction: STOP ALL ACTIVES. For 72 hours, use ONLY gentle cleanser + plain moisturizer + mineral SPF. NO acids, retinoids, Vitamin C, exfoliants, or essential oils. After 72h, reintroduce ONE product per 14 days.

Emergency stop signals: hives, swelling, blistering, persistent burning, or breathing difficulty — seek emergency care.

Troubleshooting Guide
If You Experience Likely Cause Solution
Persistent stickiness Formula's added peptide/ester load vs. the plain Serum Use less product, wait the full 1-3 minutes, or switch to the plain Serum if it bothers you
Pilling Layer applied too soon after Wait longer; reduce layers before this serum
Stinging Barrier compromise or overuse Reduce frequency; repair barrier first if persistent
Breakout weeks 2-6 Purging vs. reaction See Results Timeline for the difference
Dryness/flaking Over-exfoliation from the quadruple-acid load Add richer moisturizer, reduce frequency, 72-Hour Reset if severe
Common Mistakes to Avoid

1) Starting here instead of the plain One-Day Serum if you're new to acids. 2) Using it every night instead of 3x/week max. 3) Skipping SPF the next morning. 4) Layering a second peptide serum immediately after, which compounds the pH-vs-peptide tension already built into this formula. 5) Rubbing rather than patting, which increases friction irritation.

Usage Economics (How long it lasts)

Usage math: at 2-3 drops per use, a 30ml bottle holds approximately 300-450 uses.

Lifespan: used 3x/week, one bottle lasts roughly 6-8 months; overusing it nightly would deplete it in under 3 months while increasing barrier-damage risk.

Reorder timing: begin reordering about 2 weeks before estimated depletion.

Complete Your Routine (Exact routine + pairings)

This is the advanced-tier step in a Zero Pore routine — for someone who has already built tolerance to the plain One-Day Serum and wants the added quadruple-acid/peptide formula. It sits in the exfoliation lane of your PM routine, after cleansing, before moisturizer.

AM: 1) Gentle cleanse, 2) Hydrating toner (optional), 3) Moisturizer, 4) SPF50+ PA++++, mandatory. PM (acid nights, up to 3x/week): 1) Double cleanse if needed, 2) Zero Pore One-Day Peptide Serum — 2-3 drops, pressed in, wait 1-3 minutes, 3) Moisturizer. PM (recovery nights): cleanse, hydrating toner, barrier-support moisturizer only.

If you're new to acids entirely: start with the plain Zero Pore One-Day Serum for 4-6 weeks before graduating to this one. If your skin is barrier-compromised: pause entirely and use only gentle cleanser plus a barrier cream first. If you're already running a separate peptide serum: don't layer it the same night as this one — the acid/peptide tension is already built into this formula, adding more peptide on top doesn't compound the benefit and may irritate.

Stock-true bundle — "Zero Pore Overnight Set": Zero Foam Cleanser + this serum + Zero Pore One-Day Cream + Zero Pore Moisture Sun Serum — verified in stock.

After purchasing, you will receive our skincare education email series covering this product in depth.

The recommendations above are based on formulation synergy with Zero Pore One-Day Peptide Serum, not on margin or stock levels. If a pairing does not exist in our catalog, we say so. If you already own a product that fills the same role, use what you have first.

Is This the Best Choice? (Mindful alternatives)

If you want peptide support without the acid load, Medicube's own Hyaluronic Multi Peptide Serum 30ml (verified in stock) delivers 13 named peptides with Sodium Hyaluronate and Niacinamide and zero exfoliating acids — a genuinely gentler alternative for firmness-focused goals without the exfoliation risk.

Why Choose This Over the Alternative?

Choose the One-Day Peptide Serum over Hyaluronic Multi Peptide Serum if you need pore-clearing exfoliation and firmness support in one step — the Multi Peptide Serum addresses hydration/firmness only, with no exfoliating acids at all.

Upgrade Axis What's better in Peptide Serum Trade-off Who benefits
Pathway coverage Combines exfoliation + peptide signaling in one step Higher irritation risk than a pure peptide serum Users with both congestion AND firmness concerns
Convenience One product instead of two separate steps Less flexibility to use peptides on non-acid nights Simplified routines

Upgrade if: you have genuine pore congestion AND want a firming angle; you already tolerate acid exfoliants well.

Don't upgrade if: your primary concern is pure hydration/firmness with minimal congestion — the Multi Peptide Serum alone, with zero acids, is the lower-risk, sufficient choice.

Graduation Pathway

The full ladder: Zero Pore Pad Mild (gentle PHA-only) → Zero Pore Pad 2.0 (4.5% Lactic + 0.45% Salicylic) → Zero Pore One-Day Serum (15.2% triple acid) → this serum (quadruple acid + peptide complex, the top of the family's strength ladder).

The No-Buy Redundancy Check

This product's PRIMARY function is: chemical exfoliation plus peptide firming support. You do NOT need this if you already own the plain One-Day Serum AND a separate peptide serum, since this product's role is largely to combine what those two already do.

Inventory audit: check for an already-open acid serum or peptide serum with overlapping function before buying this one.

Stacking assessment: against the plain One-Day Serum — No Benefit if run concurrently (same acid lane, redundant). Against Hyaluronic Multi Peptide Serum — Marginal Benefit if you already own both, since this product's own peptide fraction already covers similar ground.

Sourcing and Authenticity

This product is sourced through authorized Korean distributors — primarily Craver Co., Ltd (South Korea), alongside other verified distribution partners. Craver is a major Korean beauty distributor and the parent company of SKIN1004, handling authorized distribution for multiple K-beauty brands. All products are shipped directly to Mauritius via verified channels.

For comprehensive information about how we verify authenticity, our layered verification system, and how to check your product at home, visit our dedicated Authenticity and Trust page.

Quick verification tips: genuine Medicube packaging carries a QR code on the inner box that resolves to medicubeverify.com with a green checkmark; check for a clean, legible embossed batch code; label print quality should be sharp with no spelling errors.

About Medicube
Attribute Detail
Brand Name Medicube
Parent Company APR Corporation (KRX:278470), founded Seoul 2014, public on the Korea Exchange since 2024
Founded 2016
Headquarters Seoul, South Korea
Hero Ingredient PDRN across its flagship line — this Zero Pore family is a separate, acid-focused pore-care sub-line

Medicube positions itself as a "medical beauty" brand. This peptide variant illustrates the brand's pattern of layering marketing-forward ingredient names (a "10-peptide complex," "quadruple acid") onto an existing formula — some of which we could independently confirm in the INCI and some (Copper Tripeptide-1, Acetyl Hexapeptide-1) we could not this round, worth knowing as a shopper rather than taking every marketed name at face value.

Genuine Community Experiences

A Hwahae reviewer reported their skin felt "more elastic and firm and bouncy" after use — a positive result consistent with the marketed peptide-firming angle, though individual and not independently verified.

Another Hwahae reviewer described the texture as "extremely sticky even after applying cream on top," recommending it as a PM-only treatment rather than a pre-makeup step — this contrasts with at least one plain-Serum reviewer who used that sibling product successfully as a makeup primer, suggesting the peptide variant's texture genuinely differs and reads stickier for more users.

Common praise theme: improved firmness/bounce reported by some users. Common complaint theme: stickier finish than the plain Serum, more consistently reported across reviewers for this specific variant.

Packaging and Practical Details
Attribute Detail
Primary Packaging Glass or PET dropper bottle, 30ml
Closure Type Glass dropper
Hygiene Rating Good — dropper limits air/finger contact
Travel-Friendly Yes, under standard 100ml liquid limits

Sustainability: glass components are recyclable through standard glass recycling where available in Mauritius; separate the dropper's rubber and plastic parts first. Not a refillable format.

Frequently Asked Questions

How is this different from the plain Zero Pore One-Day Serum? This variant adds LHA as a fourth acid and a marketed 10-peptide complex on the same triple-acid, 2% Niacinamide base — it's the "upgraded" version for those who've already built tolerance.

Should I start here or with the plain Serum? Start with the plain Serum if you're new to acid exfoliants; this variant is the graduated, stronger option.

Does it really contain copper peptide (GHK-Cu)? The brand's marketing names Copper Tripeptide-1, but it was not found by exact INCI name in this research pass — treat that specific ingredient claim as unresolved rather than confirmed.

Can I combine it with a separate peptide serum? Not the same night — the formula already combines acids with peptides internally; adding a second peptide product on top doesn't compound the benefit.

Why does it feel stickier than the regular serum? The added ester/peptide load (including Cetyl Palmitate, not present in the plain Serum) gives this variant a richer, tackier finish per multiple independent reviews.

Glossary
LHA
Lipohydroxy acid (Capryloyl Salicylic Acid) — a larger-molecule, gentler cousin of salicylic acid.
Peptide
A short chain of amino acids that signals skin cells to perform specific functions, like supporting firmness.
Oligopeptide-1
A peptide functioning as an EGF (epidermal growth factor) analog, signaling skin cells to renew.
Copper peptide (GHK-Cu)
A copper-bound tripeptide studied for skin-repair signaling — its presence in this specific formula is unconfirmed by INCI name.
AHA / BHA / PHA
Alpha, beta, and polyhydroxy acids — three exfoliant families that work at different depths and molecule sizes.
Barrier
The skin's outermost protective layer; when damaged it causes stinging, tightness, and flaking.
The Adilsons Promise

Every product sold by Adilsons Beauty is 100% genuine, sourced through authorized Korean distribution channels. Full details on our verification system: Authenticity and Trust.

Our team is available to help you build a routine, troubleshoot reactions, and answer ingredient questions. WhatsApp: +230 5 778 2336.

For in-depth skincare education, visit our blog at adilsons.mu/blogs/k-beauty or subscribe to our email to get our guided education series delivered to your inbox.

Delivery and Returns — Mauritius

Coverage: Island-wide delivery (Mauritius).

Processing and Timing: Orders process in 1-2 business days; usually ready by Day 3 for pickup by our delivery partners/regional team. Partner collection can take up to 1 week. After pickup, delivery typically takes 1-5 business days (weekdays only).

Express: May be available by region; request on WhatsApp: +230 5 778 2336.

Liquids/Sensitive Items: Serums, toners, liquid makeup (and kits containing liquids) are pickup or door-to-door only; checkout enforces this.

Scheduling: Deliveries run by region on set schedules; we will contact you the evening before.

Pickup: Citadelle Mall pickup available.

Returns: No change-of-mind exchanges.

Refunds (Summary): For defective/damaged on receipt (report within 48h), wrong item, or manufacturing defect within 6 months. Refunds via bank transfer (7-10 business days); card refunds may incur a 5% processor fee (fee not charged for defects/order errors). Opened skincare/personal-care items are non-returnable (except if damaged on delivery).

Source of Truth: This is a quick snapshot. If anything differs, the policy pages are final.

Store Policies: For the most up-to-date information, please review our Shipping Policy and Refund Policy.

The Final Verdict

Best for: someone who has already used and tolerated the plain Zero Pore One-Day Serum (or an equivalent acid product) well and wants an added peptide-firming angle in the same overnight step.

Key benefits: confirmed signaling peptides (Oligopeptide-1/2/3, Acetyl Octapeptide-3), broader four-acid exfoliation coverage via LHA, fragrance-free, shares the family's 2% Niacinamide.

Keep in mind: two marketed peptide names weren't confirmed by INCI in this research pass, texture reads stickier than the plain Serum per multiple reviewers, and this is the highest-risk, highest-strength product in the Zero Pore One-Day family — not a first acid serum.

Oncology and Treatment-Sensitized Skin

Assessment: Not Suitable. Although fragrance-free, the quadruple-acid load plus active peptide signaling ingredients make this the least appropriate product in the family for treatment-sensitized skin, which is typically more fragile and slower to heal.

A gentler barrier-support option, such as PDRN Pink Hyaluronic Moisturizing Cream, is a more appropriate category during active treatment.

Consult your oncology care team before introducing any new skincare products during treatment.

Phased Onboarding (Safe introduction schedule)

Quick version: Week 1-2, introduce alone at 1x/week and monitor. Week 3-4, increase to 2x/week if stable. Week 5+, hold at up to 3x/week maximum. If irritation appears, use the 72-Hour Barrier Reset rather than pushing through.

Phase Duration Frequency Amount
Introduction Weeks 1-2 1x/week 2 drops
Building Tolerance Weeks 3-4 2x/week 2-3 drops
Maintenance Week 5+ Up to 3x/week 2-3 drops

This product must be introduced as the ONLY new product. Wait 14 days before adding anything else.

Environmental Defense and Lifestyle Factors

AC/humidity swing interaction: this serum's hyaluronic acid content can pull moisture from deeper skin layers rather than the (dry) surrounding air during long AC exposure — always follow with a proper moisturizer.

Skin Microbiome and This Product

Impact: Neutral-to-Supportive. The formula contains Lactobacillus Ferment and Lactobacillus Ferment Lysate — POSTBIOTICS, beneficial metabolites from fermentation. You are not applying live bacteria; the yeasty/fermented character some ingredients carry is normal and indicates genuine ferment filtrate, not spoilage.

Your First 30 Days (Week-by-week)
Week Frequency Focus
1 1x Confirm no burning/stinging beyond mild tingling
2 1x Watch for purging in usual breakout zones
3 2x Increase only if calm through Week 2
4 2-3x (settle into maintenance) Assess visible texture and firmness change

End of Week 2 decision point: any persistent redness or burning? YES — stay at Week 1-2 frequency for 2 more weeks. NO — proceed to Week 3.

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